Standard

Primary open angle glaucoma (MTAG)

near MYO16 · rs9587617

Where this position leads

Condition: Glaucoma

rs9587617 Condition: Glaucoma Glaucoma Condition rs9587617 rs9587617 near MYO16

What the study found

Who was studied at least 29,241 European ancestry cases, at least 350,181 European ancestry controls (MTAG boosted by vertical cup-to-disc ratio and intraocular pressure samples).

The effect Each copy of the T allele shifted the measure 0.0665 lower (95% confidence interval 0.047-0.086); p = 1 × 10−11.

Where it sits Chromosome 13, band 13q33.3 — between genes, 25.6 kb from MYO16.

What each result means

C/C No copy of the version the research linked to Primary open angle glaucoma (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Primary open angle glaucoma (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Primary open angle glaucoma (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9587617

What is rs9587617?

rs9587617 is a single position in the genome, in or near the near MYO16 gene. Published research associates it with primary open angle glaucoma (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9587617 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs9587617 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9587617 come from?

GWAS Catalog, Nature genetics 2023, PMID:37386247. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Primary open angle glaucoma (MTAG) (rs9587617). MyGeneLog™. https://www.mygenelog.com/variants/rs9587617

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