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Who was studied 121,172 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0294 SD unit lower (95% confidence interval 0.02-0.039); p = 7 × 10−10.
How common The A allele had a frequency of about 75% in the people studied.
Where it sits Chromosome 13, band 13q14.2 — in an intron of RCBTB1.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Refractive error compared to the general population.
A/CPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Refractive error.
C/CPublished research associates this genotype with typical/baseline likelihood of Refractive error — no copies of the reported risk allele.
Nature genetics · 2026 · PMID 42009823 · open access
Questions about rs9568257
What is rs9568257?
rs9568257 is a single position in the genome, in or near the RCBTB1 gene. Published research associates it with refractive error. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9568257 linked to?
On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.
Does having rs9568257 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9568257 come from?
GWAS Catalog, Nature genetics 2026, PMID:42009823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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