Standard

Primary open angle glaucoma (multi-trait analysis)

near MYO16 · rs9559369

Where this position leads

Condition: Glaucoma

rs9559369 Condition: Glaucoma Glaucoma Condition rs9559369 rs9559369 near MYO16

What the study found

Who was studied at least 29,241 European ancestry cases, at least 350,181 European ancestry controls (MTAG boosted by vertical cup-to-disc ratio and intraocular pressure samples), 6,935 Asian ancestry cases, 39,588 Asian ancestry controls, 3,281 African ancestry cases, 2,791 African ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0594 higher (95% confidence interval 0.042-0.076); p = 8 × 10−12.

Where it sits Chromosome 13, band 13q33.3 — between genes, 24.6 kb from MYO16.

What each result means

A/A Two copies of the version the research linked to Primary open angle glaucoma (multi-trait analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Primary open angle glaucoma (multi-trait analysis). That is a smaller link than two copies.
G/G No copy of the version the research linked to Primary open angle glaucoma (multi-trait analysis). This is the starting point the study compared everyone against.
Source

Questions about rs9559369

What is rs9559369?

rs9559369 is a single position in the genome, in or near the near MYO16 gene. Published research associates it with primary open angle glaucoma (multi-trait analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9559369 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs9559369 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9559369 come from?

GWAS Catalog, Nature genetics 2023, PMID:37386247. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Primary open angle glaucoma (multi-trait analysis) (rs9559369). MyGeneLog™. https://www.mygenelog.com/variants/rs9559369

← See all variants