2 422234223222Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity3Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total42Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,157 European ancestry cases, 1,150 European ancestry controls; replicated in 7,892 European ancestry cases, 5,998 European ancestry controls, 678 Japanese ancestry cases, 336 Japanese ancestry controls.
The effect
Each copy of the A allele carried 4.31 times the odds of Age-related macular degeneration (95% confidence interval 2.76-6.87); p = 2 × 10−8.
How common The A allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of C2-AS1.
What each result means
A/ATwo copies of the version the research linked to Age-related macular degeneration. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Age-related macular degeneration. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Age-related macular degeneration. This is the starting point the study compared everyone against.
Proceedings of the National Academy of Sciences of the United States of America · 2010 · PMID 20385819
Questions about rs9380272
What is rs9380272?
rs9380272 is a single position in the genome, in or near the CFB gene. Published research associates it with age-related macular degeneration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9380272 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
Does having rs9380272 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9380272 come from?
GWAS Catalog, Proc Natl Acad Sci U S A 2010, PMID:20385819. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 422234223222Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity3Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total42Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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