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Tissue factor pathway inhibitor levels

F5 · rs9332629

Where this position leads

Drug: Combined hormonal contraceptives

rs9332629 Drug: Combined hormonal contraceptives Combined hormonal contraceptives Drug rs9332629 rs9332629 F5

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.413 lower (95% confidence interval 0.36-0.46); p = 1 × 10−56.

How common The T allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 1, band 1q24.2 — in an intron of F5.

What each result means

C/C No copy of the version the research linked to Tissue factor pathway inhibitor levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Tissue factor pathway inhibitor levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Tissue factor pathway inhibitor levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9332629

What is rs9332629?

rs9332629 is a single position in the genome, in or near the F5 gene. Published research associates it with tissue factor pathway inhibitor levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs9332629 affect how medicines work?

F5 carries pharmacogenomic findings for Combined hormonal contraceptives. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs9332629 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9332629 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Tissue factor pathway inhibitor levels (rs9332629). MyGeneLog™. https://www.mygenelog.com/variants/rs9332629

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