1 2911712314Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others14Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 6,687 European ancestry cases, 155,514 European ancestry controls, 204 South Asian ancestry cases, 4,916 South Asian ancestry controls, 272 African British cases, 4,831 African British controls, 22 East Asian ancestry cases, 873 East Asian ancestry controls, 144 mixed ancestry cases, 3,427 mixed ancestry controls; replicated in 3,836 European ancestry cases, 48,065 European ancestry controls, 411 Hispanic cases, 4,778 Hispanic controls, 441 East Asian ancestry cases, 4,034 East Asian ancestry controls, 298 African American cases, 1,549 African American controls.
The effect
Each copy of the C allele carried 1.16 times the odds of Glaucoma (primary open-angle) (95% confidence interval 1.12–1.20); p = 2 × 10−18.
Where it sits Chromosome 4, band 4p16.1 — in an intron of AFAP1.
What each result means
C/CTwo copies of the version the research linked to Glaucoma (primary open-angle). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Glaucoma (primary open-angle). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Glaucoma (primary open-angle). This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 29891935 · open access
Questions about rs9330348
What is rs9330348?
rs9330348 is a single position in the genome, in or near the AFAP1 gene. Published research associates it with glaucoma (primary open-angle). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9330348 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs9330348 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9330348 come from?
GWAS Catalog, Nat Commun 2018, PMID:29891935. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 2911712314Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others14Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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