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Who was studied 148,726 European ancestry cases, 965,732 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.0981 higher (95% confidence interval 0.079-0.117); p = 6 × 10−24.
How common The C allele had a frequency of about 11% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — between genes, 18.6 kb from HLA-DQB1.
What each result means
C/CTwo copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
Nature genetics · 2020 · PMID 32541925 · open access
Questions about rs9275184
What is rs9275184?
rs9275184 is a single position in the genome, in or near the near HLA-DQB1 gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9275184 linked to?
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs9275184 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9275184 come from?
GWAS Catalog, Nature genetics 2020, PMID:32541925. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 2 diabetes (rs9275184). MyGeneLog™. https://www.mygenelog.com/variants/rs9275184