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Leprosy

near HLA-DRB1 · rs9271011

Where this position leads

Condition: Leprosy

rs9271011 Condition: Leprosy Leprosy Condition rs9271011 rs9271011 near HLA-DRB1

What the study found

Who was studied 2,118 Chinese ancestry cases, 2,822 Chinese ancestry controls; replicated in 842 Chinese ancestry cases, 925 Chinese ancestry controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 4 × 10−50.

Where it sits Chromosome 6, band 6p21.32 — between genes, 17.1 kb from HLA-DRB1.

What each result means

A/A No copy of the version the research linked to Leprosy. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Leprosy. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Leprosy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9271011

What is rs9271011?

rs9271011 is a single position in the genome, in or near the near HLA-DRB1 gene. Published research associates it with leprosy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9271011 linked to?

On MyGeneLog this position is linked to Leprosy. The research behind each link, and its sources, are set out on that condition page.

Does having rs9271011 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9271011 come from?

GWAS Catalog, Human molecular genetics 2022, PMID:35512355. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Leprosy (rs9271011). MyGeneLog™. https://www.mygenelog.com/variants/rs9271011

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