Gene Knowledge Graph
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Gene

HLA-DRB1

HLA-DRB1 is a gene. This site has 48 published variants inside it and 119 near it, each from a published genetic study, joining it to 30 condition pages.

What prescribing experts say about HLA-DRB1 (2)

CPIC, the international group that writes gene-based prescribing guidelines, rates how strong the evidence is for each gene and medicine, from A (strong enough to change the prescription) to D (weak or conflicting). Every rating is shown, the weak ones included, so you can see where the evidence stops.

Source: CPIC (Clinical Pharmacogenetics Implementation Consortium), public domain (CC0), copy kept on this site and refreshed weekly.

US drug labels that name HLA-DRB1 (1)

The FDA keeps a list of medicine labels that mention a gene. These are the ones that name HLA-DRB1. Where this site has a page on the medicine, the name links to it; otherwise it opens the label on DailyMed. A label naming a gene does not always mean a test or a dose change: for many it is one line about how the body clears the drug.

Source: FDA Table of Pharmacogenomic Biomarkers in Drug Labeling, current as of 12 August 2026.

Conditions it is linked to

Variants inside HLA-DRB1 (48)

Variants near HLA-DRB1 (119)

Positions outside the gene, filed under it because it is the closest. A variant near a gene does not always act through it.

See HLA-DRB1 with everything it connects to on the Gene Knowledge Graph, or as data at /api/v1/genes/HLA-DRB1.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

HLA-DRB1 gene. MyGeneLog™. https://www.mygenelog.com/genes/HLA-DRB1

A gene page gathers published research; it is not a test result and not medical advice. If a gene matters to your health, talk to a doctor or a genetic counsellor.