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Monocyte count

near HLA-B · rs9265956

Where this position leads

Conditions: Monocyte Count, Blood Cell Counts

rs9265956 Condition: Monocyte Count Monocyte Count Condition Condition: Blood Cell Counts Blood Cell Counts Condition rs9265956 rs9265956 near HLA-B

What the study found

Who was studied 234,690 European ancestry individuals; replicated in 100,494 European ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 2 × 10−45.

How common The T allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 6.3 kb from HLA-B.

What each result means

C/C No copy of the version the research linked to Monocyte count. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Monocyte count. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Monocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9265956

What is rs9265956?

rs9265956 is a single position in the genome, in or near the near HLA-B gene. Published research associates it with monocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9265956 linked to?

On MyGeneLog this position is linked to Monocyte Count, Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs9265956 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9265956 come from?

GWAS Catalog, American journal of human genetics 2021, PMID:34469753. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Monocyte count (rs9265956). MyGeneLog™. https://www.mygenelog.com/variants/rs9265956

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