C/CPublished research associates this genotype with typical/baseline likelihood of Type 1 diabetes with low genetic risk score — no copies of the reported risk allele. (GWAS Catalog, Commun Biol 2021, PMID:34302048)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Type 1 diabetes with low genetic risk score. (GWAS Catalog, Commun Biol 2021, PMID:34302048)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Type 1 diabetes with low genetic risk score compared to the general population. (GWAS Catalog, Commun Biol 2021, PMID:34302048)
rs857786 is a single position in the genome, in or near the MNDA gene. Published research associates it with type 1 diabetes with low genetic risk score. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs857786 linked to?
On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs857786 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs857786 come from?
GWAS Catalog, Commun Biol 2021, PMID:34302048. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.