Sensitive

Type 1 diabetes with low genetic risk score

MNDA · rs857786

Where this position leads

Condition: Type 1 Diabetes

rs857786 Condition: Type 1 Diabetes Type 1 Diabetes Condition rs857786 rs857786 MNDA

What the study found

Who was studied 957 European ancestry cases, 12,323 European ancestry controls.

The effect Each copy of the T allele carried 1.32 times the odds of Type 1 diabetes with low genetic risk score (95% confidence interval 1.203-1.452); p = 6 × 10−9.

Where it sits Chromosome 1, band 1q23.1 — inside OR6N1.

What each result means

C/C No copy of the version the research linked to Type 1 diabetes with low genetic risk score. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Type 1 diabetes with low genetic risk score. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Type 1 diabetes with low genetic risk score. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs857786

What is rs857786?

rs857786 is a single position in the genome, in or near the MNDA gene. Published research associates it with type 1 diabetes with low genetic risk score. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs857786 linked to?

On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs857786 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs857786 come from?

GWAS Catalog, Commun Biol 2021, PMID:34302048. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 1 diabetes with low genetic risk score (rs857786). MyGeneLog™. https://www.mygenelog.com/variants/rs857786

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