Standard

Fluid intelligence

FANCL · rs848283

Where this position leads

Condition: Intelligence

rs848283 Condition: Intelligence Intelligence Condition rs848283 rs848283 FANCL

What the study found

Who was studied 182,798 British ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0699 higher; p = 1 × 10−9.

How common The T allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 2, band 2p16.1 — in an intron of FANCL.

What each result means

C/C No copy of the version the research linked to Fluid intelligence. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Fluid intelligence. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Fluid intelligence. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs848283

What is rs848283?

rs848283 is a single position in the genome, in or near the FANCL gene. Published research associates it with fluid intelligence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs848283 linked to?

On MyGeneLog this position is linked to Intelligence. The research behind each link, and its sources, are set out on that condition page.

Does having rs848283 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs848283 come from?

GWAS Catalog, Communications biology 2026, PMID:42092107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Fluid intelligence (rs848283). MyGeneLog™. https://www.mygenelog.com/variants/rs848283

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