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Monocyte count

IKZF1 · rs80271829

Where this position leads

Conditions: Monocyte Count, Blood Cell Counts

rs80271829 Condition: Monocyte Count Monocyte Count Condition Condition: Blood Cell Counts Blood Cell Counts Condition rs80271829 rs80271829 IKZF1

What the study found

Who was studied 170,721 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.05 lower (95% confidence interval 0.037-0.062); p = 4 × 10−15.

How common The C allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 7, band 7p12.2 — in an intron of IKZF1.

What each result means

C/C Two copies of the version the research linked to Monocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Monocyte count. That is a smaller link than two copies.
T/T No copy of the version the research linked to Monocyte count. This is the starting point the study compared everyone against.
Source

Questions about rs80271829

What is rs80271829?

rs80271829 is a single position in the genome, in or near the IKZF1 gene. Published research associates it with monocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs80271829 linked to?

On MyGeneLog this position is linked to Monocyte Count, Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs80271829 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs80271829 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Monocyte count (rs80271829). MyGeneLog™. https://www.mygenelog.com/variants/rs80271829

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