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Who was studied 3,037,499 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.00906 lower (95% confidence interval 0.0061-0.012); p = 3 × 10−9.
How common The T allele had a frequency of about 14% in the people studied.
Where it sits Chromosome 1, band 1p21.3 — in an intron of DPYD.
What each result means
C/CNo copy of the version the research linked to Educational attainment. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Educational attainment. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Educational attainment. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2022 · PMID 35361970 · open access
Questions about rs80216782
What is rs80216782?
rs80216782 is a single position in the genome, in or near the DPYD gene. Published research associates it with educational attainment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs80216782 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does rs80216782 affect how medicines work?
DPYD carries pharmacogenomic findings for Fluoropyrimidines. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs80216782 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs80216782 come from?
GWAS Catalog, Nature genetics 2022, PMID:35361970. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 312Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total3Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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