Sensitive

Plasma 1-linoleoyl-GPG (18:2)* levels in chronic kidney disease

SLCO1B1 · rs7969341

Where this position leads

Drugs: Statins, Ticagrelor

rs7969341 Drug: Statins Statins Drug Drug: Ticagrelor Ticagrelor Drug rs7969341 rs7969341 SLCO1B1

What the study found

Who was studied 4,568 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.209 higher (95% confidence interval 0.17-0.24); p = 8 × 10−32.

How common The G allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 12, band 12p12.1 — in an intron of SLCO1B1.

What each result means

A/A No copy of the version the research linked to Plasma 1-linoleoyl-GPG (18:2)* levels in chronic kidney disease. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Plasma 1-linoleoyl-GPG (18:2)* levels in chronic kidney disease. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Plasma 1-linoleoyl-GPG (18:2)* levels in chronic kidney disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7969341

What is rs7969341?

rs7969341 is a single position in the genome, in or near the SLCO1B1 gene. Published research associates it with plasma 1-linoleoyl-gpg (18:2)* levels in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs7969341 affect how medicines work?

SLCO1B1 carries pharmacogenomic findings for Statins, Ticagrelor. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs7969341 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7969341 come from?

GWAS Catalog, Nature genetics 2023, PMID:37277652. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Plasma 1-linoleoyl-GPG (18:2)* levels in chronic kidney disease (rs7969341). MyGeneLog™. https://www.mygenelog.com/variants/rs7969341

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