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Lysophosphatidylethanolamine_20:4_[M-H]1- levels

SLCO1B1 · rs7957274

Where this position leads

Drugs: Statins, Ticagrelor

rs7957274 Drug: Statins Statins Drug Drug: Ticagrelor Ticagrelor Drug rs7957274 rs7957274 SLCO1B1

What the study found

Who was studied 13,814 British ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.141 lower (95% confidence interval 0.11-0.17); p = 1 × 10−22.

Where it sits Chromosome 12, band 12p12.1 — in an intron of SLCO1B1.

What each result means

C/C Two copies of the version the research linked to Lysophosphatidylethanolamine_20:4_[M-H]1- levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Lysophosphatidylethanolamine_20:4_[M-H]1- levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Lysophosphatidylethanolamine_20:4_[M-H]1- levels. This is the starting point the study compared everyone against.
Source

Questions about rs7957274

What is rs7957274?

rs7957274 is a single position in the genome, in or near the SLCO1B1 gene. Published research associates it with lysophosphatidylethanolamine_20:4_[m-h]1- levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs7957274 affect how medicines work?

SLCO1B1 carries pharmacogenomic findings for Statins, Ticagrelor. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs7957274 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7957274 come from?

GWAS Catalog, BMC medicine 2021, PMID:34503513. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lysophosphatidylethanolamine_20:4_[M-H]1- levels (rs7957274). MyGeneLog™. https://www.mygenelog.com/variants/rs7957274

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