LRRC43 · rs7953139
Where this position leads
Condition: Hay Fever And/or Eczema
What the study found
Who was studied 84,034 European ancestry cases, 239,773 European ancestry controls.
The effect Each copy of the C allele carried 1.04 times the odds of Hay fever and/or eczema (95% confidence interval 1.03-1.053); p = 1 × 10−11.
How common The C allele had a frequency of about 48% in the people studied.
Where it sits Chromosome 12, band 12q24.31 — inside LRRC43.
rs7953139 is a single position in the genome, in or near the LRRC43 gene. Published research associates it with hay fever and/or eczema. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Hay Fever And/or Eczema. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Human molecular genetics 2019, PMID:31361310. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Hay fever and/or eczema (rs7953139). MyGeneLog™. https://www.mygenelog.com/variants/rs7953139