0 1611248Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple4China (ByteDance, Huawei, Baidu…)0Others8Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,495,159 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0163 SD unit lower (95% confidence interval 0.011-0.022); p = 9 × 10−9.
How common The A allele had a frequency of about 8% in the people studied.
Where it sits Chromosome 14, band 14q23.2 — in an intron of GPHB5.
What each result means
A/ATwo copies of the version the research linked to Refractive error. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Refractive error. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Refractive error. This is the starting point the study compared everyone against.
Nature genetics · 2026 · PMID 42009823 · open access
Questions about rs78650279
What is rs78650279?
rs78650279 is a single position in the genome, in or near the GPHB5 gene. Published research associates it with refractive error. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs78650279 linked to?
On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.
Does having rs78650279 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs78650279 come from?
GWAS Catalog, Nature genetics 2026, PMID:42009823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1611248Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple4China (ByteDance, Huawei, Baidu…)0Others8Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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