Standard

Lp (a) levels

PLG · rs783147

What the study found

Who was studied 1,450 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.3 mg/dL lower (95% confidence interval 0.22-0.38); p = 3 × 10−17.

How common The A allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 6, band 6q26 — in an intron of PLG.

What ClinVar records

Classification Benign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2021-06-19. ClinVar record 1274066 NM_000301.5(PLG):c.787+195G>A

What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

A/A Two copies of the version the research linked to Lp (a) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Lp (a) levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Lp (a) levels. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs783147

What is rs783147?

rs783147 is a single position in the genome, in or near the PLG gene. Published research associates it with lp (a) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs783147?

Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs783147 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs783147 come from?

GWAS Catalog, Eur Heart J 2011, PMID:21900290. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lp (a) levels (rs783147). MyGeneLog™. https://www.mygenelog.com/variants/rs783147

← See all variants