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Who was studied 38,000 South Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.079 higher (95% confidence interval 0.055-0.103); p = 1 × 10−11.
Where it sits Chromosome 6, band 6p21.33 — between genes, 1.1 kb from HLA-C.
What each result means
G/GTwo copies of the version the research linked to Monocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Monocyte count. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Monocyte count. This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 39414775 · open access
Questions about rs7759127
What is rs7759127?
rs7759127 is a single position in the genome, in or near the near HLA-C gene. Published research associates it with monocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7759127 linked to?
On MyGeneLog this position is linked to Monocyte Count. The research behind each link, and its sources, are set out on that condition page.
Does having rs7759127 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7759127 come from?
GWAS Catalog, Nature communications 2024, PMID:39414775. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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