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Who was studied 349,856 European ancestry individuals, 95,119 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0147 lower (95% confidence interval 0.01-0.019); p = 2 × 10−11.
Where it sits Chromosome 6, band 6p21.2 — between genes, 3.4 kb from COX6A1P2.
What each result means
A/ATwo copies of the version the research linked to Monocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Monocyte count. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Monocyte count. This is the starting point the study compared everyone against.
rs7748197 is a single position in the genome, in or near the near COX6A1P2 gene. Published research associates it with monocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7748197 linked to?
On MyGeneLog this position is linked to Monocyte Count. The research behind each link, and its sources, are set out on that condition page.
Does having rs7748197 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7748197 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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