Urinary metabolite levels in chronic kidney disease
SLCO1B1 · rs77289848
1 2022214Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others14Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,221 cases; replicated in 406 cases.
The effect
Each copy of the A allele shifted the measure 0.579 higher (95% confidence interval 0.41-0.75); p = 2 × 10−11.
How common The A allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 12, band 12p12.1 — in an intron of SLCO1B1.
What each result means
A/ATwo copies of the version the research linked to Urinary metabolite levels in chronic kidney disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Urinary metabolite levels in chronic kidney disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Urinary metabolite levels in chronic kidney disease. This is the starting point the study compared everyone against.
rs77289848 is a single position in the genome, in or near the SLCO1B1 gene. Published research associates it with urinary metabolite levels in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs77289848 affect how medicines work?
SLCO1B1 carries pharmacogenomic findings for Statins, Ticagrelor. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs77289848 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs77289848 come from?
GWAS Catalog, Nature genetics 2020, PMID:31959995. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 2022214Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others14Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Urinary metabolite levels in chronic kidney disease (rs77289848). MyGeneLog™. https://www.mygenelog.com/variants/rs77289848