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Who was studied 20,972 Japanese ancestry cases, 240,675 Japanese ancestry controls, 7,710 European ancestry cases, 626,533 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.101 higher (95% confidence interval 0.065-0.137); p = 3 × 10−8.
How common The T allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 3, band 3q26.2 — in an intron of MECOM.
What each result means
C/CNo copy of the version the research linked to Gastric ulcer. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Gastric ulcer. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Gastric ulcer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2023 · PMID 38036781 · open access
Questions about rs77132614
What is rs77132614?
rs77132614 is a single position in the genome, in or near the MECOM gene. Published research associates it with gastric ulcer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs77132614 linked to?
On MyGeneLog this position is linked to Gastric Ulcer. The research behind each link, and its sources, are set out on that condition page.
Does having rs77132614 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs77132614 come from?
GWAS Catalog, Nature genetics 2023, PMID:38036781. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 29114102227Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot10Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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