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Who was studied 169 African American or Afro-Caribbean, African ancestry cases, 8,368 African American or Afro-Caribbean, African ancestry controls, 1,210 East Asian ancestry cases, 254,409 East Asian ancestry controls, 9,411 European ancestry cases, 1,057,284 European ancestry controls, 319 Hispanic or Latin American cases, 14,452 Hispanic or Latin American controls, 51 South Asian ancestry cases, 21,897 South Asian ancestry controls.
The effect
Each copy of the T allele carried 1.29 times the odds of Idiopathic pulmonary fibrosis (95% confidence interval 1.18-1.42); p = 3 × 10−8.
Where it sits Chromosome 4, band 4q32.1 — between genes, 114.9 kb from LINC02233.
What each result means
A/ANo copy of the version the research linked to Idiopathic pulmonary fibrosis. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Idiopathic pulmonary fibrosis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Idiopathic pulmonary fibrosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Cell genomics · 2022 · PMID 36777997 · open access
Questions about rs76537958
What is rs76537958?
rs76537958 is a single position in the genome, in or near the near LINC02233 gene. Published research associates it with idiopathic pulmonary fibrosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs76537958 linked to?
On MyGeneLog this position is linked to Idiopathic Pulmonary Fibrosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs76537958 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs76537958 come from?
GWAS Catalog, Cell genomics 2022, PMID:36777997. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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