0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 232 Hispanic or Latin American cases, 59,553 Hispanic or Latin American controls, 2,074 European ancestry cases, 448,199 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 3.34 lower (95% confidence interval 3.32-3.37); p = 6 × 10−12.
How common The C allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 8, band 8q22.2 — in an intron of VPS13B.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Meniere's disease (PheCode 386.1) compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Meniere's disease (PheCode 386.1).
T/TPublished research associates this genotype with typical/baseline likelihood of Meniere's disease (PheCode 386.1) — no copies of the reported risk allele.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs76416960
What is rs76416960?
rs76416960 is a single position in the genome, in or near the VPS13B gene. Published research associates it with meniere's disease (phecode 386.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs76416960 linked to?
On MyGeneLog this position is linked to Meniere's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs76416960 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs76416960 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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