Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio
KLF12 · rs75689443
0 7124Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 98,316 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.242 higher (95% confidence interval 0.18-0.31); p = 7 × 10−13.
How common The A allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 13, band 13q22.1 — in an intron of KLF12.
What each result means
A/ATwo copies of the version the research linked to Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio. This is the starting point the study compared everyone against.
Ophthalmology science · 2024 · PMID 39091897 · open access
Questions about rs75689443
What is rs75689443?
rs75689443 is a single position in the genome, in or near the KLF12 gene. Published research associates it with free cholesterol to cholesteryl esters in medium vldl ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs75689443 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
Does having rs75689443 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75689443 come from?
GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 7124Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio (rs75689443). MyGeneLog™. https://www.mygenelog.com/variants/rs75689443