0 25112318Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others18Total25Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 91,105 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.042 SD units higher (95% confidence interval 0.028-0.056); p = 2 × 10−10.
How common The A allele had a frequency of about 86% in the people studied.
Where it sits Chromosome 1, band 1p21.3 — in an intron of DPYD.
What each result means
A/ATwo copies of the version the research linked to Sleep duration. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Sleep duration. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Sleep duration. This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 30531941 · open access
Questions about rs75641275
What is rs75641275?
rs75641275 is a single position in the genome, in or near the DPYD gene. Published research associates it with sleep duration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs75641275 linked to?
On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.
Does rs75641275 affect how medicines work?
DPYD carries pharmacogenomic findings for Fluoropyrimidines. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs75641275 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75641275 come from?
GWAS Catalog, Nat Commun 2018, PMID:30531941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 25112318Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others18Total25Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.