Standard

Refractive error

RASGRF1 · rs755362

Where this position leads

Condition: Myopia

rs755362 Condition: Myopia Myopia Condition rs755362 rs755362 RASGRF1

What the study found

Who was studied 121,172 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0457 SD unit higher (95% confidence interval 0.038-0.054); p = 5 × 10−28.

How common The A allele had a frequency of about 49% in the people studied.

Where it sits Chromosome 15, band 15q25.1 — in an intron of RASGRF1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Refractive error compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Refractive error.
G/G Published research associates this genotype with typical/baseline likelihood of Refractive error — no copies of the reported risk allele.
Source

Questions about rs755362

What is rs755362?

rs755362 is a single position in the genome, in or near the RASGRF1 gene. Published research associates it with refractive error. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs755362 linked to?

On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.

Does having rs755362 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs755362 come from?

GWAS Catalog, Nature genetics 2026, PMID:42009823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Refractive error (rs755362). MyGeneLog™. https://www.mygenelog.com/variants/rs755362

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