Lipoprotein-associated phospholipase A2 activity and mass
CELSR2 · rs7528419
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 12,126 European ancestry individuals, 1,538 individuals.
The effect
Each copy of the A allele shifted the measure 0.035 higher (95% confidence interval 0.027-0.043); p = 1 × 10−17.
How common The A allele had a frequency of about 79% in the people studied.
Where it sits Chromosome 1, band 1p13.3 — in the 3′ untranslated region of CELSR2.
What each result means
A/ATwo copies of the version the research linked to Lipoprotein-associated phospholipase A2 activity and mass. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Lipoprotein-associated phospholipase A2 activity and mass. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Lipoprotein-associated phospholipase A2 activity and mass. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs7528419
What is rs7528419?
rs7528419 is a single position in the genome, in or near the CELSR2 gene. Published research associates it with lipoprotein-associated phospholipase a2 activity and mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs7528419?
Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (3 papers), blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs7528419 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7528419 come from?
GWAS Catalog, Eur Heart J 2011, PMID:22003152. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Lipoprotein-associated phospholipase A2 activity and mass (rs7528419). MyGeneLog™. https://www.mygenelog.com/variants/rs7528419