Sensitive

Hodgkin's disease (PheCode 201)

near LINC02838 · rs75229018

Where this position leads

Condition: Hodgkin's Disease

rs75229018 Condition: Hodgkin's Disease Hodgkin's Disease Condition rs75229018 rs75229018 near LINC028…

What the study found

Who was studied 215 African American or Afro-Caribbean cases, 121,633 African American or Afro-Caribbean controls, 975 European ancestry cases, 449,793 European ancestry controls.

The effect Each copy of the C allele shifted the measure 3.37 lower (95% confidence interval 3.35-3.39); p = 6 × 10−13.

How common The C allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 7, band 7p12.3 — between genes, 31 kb from LINC02838.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hodgkin's disease (PheCode 201) compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hodgkin's disease (PheCode 201).
T/T Published research associates this genotype with typical/baseline likelihood of Hodgkin's disease (PheCode 201) — no copies of the reported risk allele.
Source

Questions about rs75229018

What is rs75229018?

rs75229018 is a single position in the genome, in or near the near LINC02838 gene. Published research associates it with hodgkin's disease (phecode 201). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs75229018 linked to?

On MyGeneLog this position is linked to Hodgkin's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs75229018 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75229018 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hodgkin's disease (PheCode 201) (rs75229018). MyGeneLog™. https://www.mygenelog.com/variants/rs75229018

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