Sensitive

Type 2 diabetes

RUFY3 · rs73824896

Where this position leads

Condition: Type 2 Diabetes

rs73824896 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs73824896 rs73824896 RUFY3

What the study found

Who was studied 2,765 Qatari ancestry cases, 8,671 Qatari ancestry controls, 180,834 European ancestry cases, 1,159,055 European ancestry controls, 180,834 East Asian ancestry cases, 1,159,055 East Asian ancestry controls, 180,834 South Asian ancestry cases, 1,159,055 South Asian ancestry controls, 180,834 African ancestry cases, 1,159,055 African ancestry controls, 180,834 Hispanic or Latin American cases, 1,159,055 Hispanic or Latin American controls.

The effect Each copy of the C allele shifted the measure 0.0463 higher (95% confidence interval 0.03-0.062); p = 2 × 10−8.

Where it sits Chromosome 4, band 4q13.3 — in an intron of RUFY3.

What each result means

C/C Two copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
T/T No copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
Source

Questions about rs73824896

What is rs73824896?

rs73824896 is a single position in the genome, in or near the RUFY3 gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73824896 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs73824896 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73824896 come from?

GWAS Catalog, BMC medical genomics 2024, PMID:38685053. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 2 diabetes (rs73824896). MyGeneLog™. https://www.mygenelog.com/variants/rs73824896

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