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Feeling fed-up

UBXN2A · rs72796402

Where this position leads

Condition: Irritable Mood

rs72796402 Condition: Irritable Mood Irritable Mood Condition rs72796402 rs72796402 UBXN2A

What the study found

Who was studied 374,971 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 6.89 z score lower; p = 6 × 10−12.

How common The A allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 2, band 2p23.3 — in an intron of UBXN2A.

What each result means

A/A Two copies of the version the research linked to Feeling fed-up. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Feeling fed-up. That is a smaller link than two copies.
G/G No copy of the version the research linked to Feeling fed-up. This is the starting point the study compared everyone against.
Source

Questions about rs72796402

What is rs72796402?

rs72796402 is a single position in the genome, in or near the UBXN2A gene. Published research associates it with feeling fed-up. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72796402 linked to?

On MyGeneLog this position is linked to Irritable Mood. The research behind each link, and its sources, are set out on that condition page.

Does having rs72796402 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72796402 come from?

GWAS Catalog, Nature communications 2018, PMID:29500382. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Feeling fed-up (rs72796402). MyGeneLog™. https://www.mygenelog.com/variants/rs72796402

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