Standard

Glaucoma

LINC01376 · rs72778322

Where this position leads

Condition: Glaucoma

rs72778322 Condition: Glaucoma Glaucoma Condition rs72778322 rs72778322 LINC01376

What the study found

Who was studied 38,064 African American or Afro-Caribbean cases, 76,856 African American or Afro-Caribbean controls, 11,570 Hispanic or Latin American cases, 45,339 Hispanic or Latin American controls, 1,446 East Asian ancestry cases, 5,057 East Asian ancestry controls, 81,303 European ancestry cases, 349,418 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.171 higher (95% confidence interval 0.13-0.21); p = 3 × 10−19.

How common The G allele had a frequency of about 98% in the people studied.

Where it sits Chromosome 2, band 2p24.1 — in an intron of LINC01376.

What each result means

A/A No copy of the version the research linked to Glaucoma. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Glaucoma. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Glaucoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs72778322

What is rs72778322?

rs72778322 is a single position in the genome, in or near the LINC01376 gene. Published research associates it with glaucoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72778322 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs72778322 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72778322 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glaucoma (rs72778322). MyGeneLog™. https://www.mygenelog.com/variants/rs72778322

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