0 1917236Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI7Microsoft · Copilot0Amazon2Apple3Others6Total19Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 388,538 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0115 higher (95% confidence interval 0.0076-0.0154); p = 6 × 10−9.
How common The T allele had a frequency of about 67% in the people studied.
Where it sits Chromosome 16, band 16p13.3 — in an intron of RBFOX1.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Subjective well-being (MTAG) — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Subjective well-being (MTAG).
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Subjective well-being (MTAG) compared to the general population.
Nature genetics · 2018 · PMID 29292387 · open access
Questions about rs716508
What is rs716508?
rs716508 is a single position in the genome, in or near the RBFOX1 gene. Published research associates it with subjective well-being (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs716508 linked to?
On MyGeneLog this position is linked to Depression (Self-Reported Symptoms). The research behind each link, and its sources, are set out on that condition page.
Does having rs716508 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs716508 come from?
GWAS Catalog, Nat Genet 2018, PMID:29292387. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1917236Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI7Microsoft · Copilot0Amazon2Apple3Others6Total19Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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