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Who was studied 373,121 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 7.31 z score lower; p = 3 × 10−13.
How common The T allele had a frequency of about 39% in the people studied.
Where it sits Chromosome 10, band 10q24.33 — in an intron of NT5C2.
What each result means
C/CNo copy of the version the research linked to Feeling nervous. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Feeling nervous. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Feeling nervous. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 29500382 · open access
Questions about rs7077291
What is rs7077291?
rs7077291 is a single position in the genome, in or near the NT5C2 gene. Published research associates it with feeling nervous. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7077291 linked to?
On MyGeneLog this position is linked to Irritable Mood. The research behind each link, and its sources, are set out on that condition page.
Does having rs7077291 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7077291 come from?
GWAS Catalog, Nature communications 2018, PMID:29500382. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 112216Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others6Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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