Standard

Subjective well-being (MTAG)

near EMX2 · rs703410

Where this position leads

Condition: Depression (Self-Reported Symptoms)

rs703410 Condition: Depression (Self-Reported Symptoms) Depression (Self-Reported Symptoms) Condition rs703410 rs703410 near EMX2

What the study found

Who was studied 388,538 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0118 higher (95% confidence interval 0.0077-0.0159); p = 2 × 10−8.

How common The A allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 10, band 10q26.11 — in an intron of EMX2OS.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Subjective well-being (MTAG) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Subjective well-being (MTAG).
G/G Published research associates this genotype with typical/baseline likelihood of Subjective well-being (MTAG) — no copies of the reported risk allele.
Source

Questions about rs703410

What is rs703410?

rs703410 is a single position in the genome, in or near the near EMX2 gene. Published research associates it with subjective well-being (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs703410 linked to?

On MyGeneLog this position is linked to Depression (Self-Reported Symptoms). The research behind each link, and its sources, are set out on that condition page.

Does having rs703410 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs703410 come from?

GWAS Catalog, Nat Genet 2018, PMID:29292387. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Subjective well-being (MTAG) (rs703410). MyGeneLog™. https://www.mygenelog.com/variants/rs703410

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