Standard

Low high density lipoprotein cholesterol levels

ABCA1 · rs7024300

What the study found

Who was studied 1,747 Saudi Arab ancestry cases, 2,335 Saudi Arab ancestry controls; replicated in 517 Saudi Arab ancestry cases, 896 Saudi Arab ancestry controls.

The effect Each copy of the T allele carried 1.45 times the odds of Low high density lipoprotein cholesterol levels (95% confidence interval 1.11-1.92); p = 1 × 10−8.

Where it sits Chromosome 9, band 9q31.1 — in an intron of ABCA1.

What ClinVar records

Classification Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-08-30. ClinVar record 1235958 NM_005502.4(ABCA1):c.2116-117G>A

What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

C/C No copy of the version the research linked to Low high density lipoprotein cholesterol levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Low high density lipoprotein cholesterol levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Low high density lipoprotein cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs7024300

What is rs7024300?

rs7024300 is a single position in the genome, in or near the ABCA1 gene. Published research associates it with low high density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs7024300?

Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs7024300 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7024300 come from?

GWAS Catalog, Clin Genet 2016, PMID:26879886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Low high density lipoprotein cholesterol levels (rs7024300). MyGeneLog™. https://www.mygenelog.com/variants/rs7024300

← See all variants