Sensitive

Multiple sclerosis

OS9 · rs701006

Where this position leads

Condition: Multiple Sclerosis

rs701006 Condition: Multiple Sclerosis Multiple Sclerosis Condition rs701006 rs701006 OS9

What the study found

Who was studied 14,802 European and unknown ancestry cases, 26,703 European and unknown ancestry controls; replicated in 32,627 European and unknown ancestry cases, 41,672 European and unknown ancestry controls.

The effect Each copy of the G allele carried 1.12 times the odds of Multiple sclerosis; p = 1 × 10−30.

Where it sits Chromosome 12, band 12q14.1 — in an intron of OS9-AS1.

What each result means

A/A No copy of the version the research linked to Multiple sclerosis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Multiple sclerosis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Multiple sclerosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs701006

What is rs701006?

rs701006 is a single position in the genome, in or near the OS9 gene. Published research associates it with multiple sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs701006 linked to?

On MyGeneLog this position is linked to Multiple Sclerosis. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs701006?

Subjects that appear in the title or abstract of the same papers as this rsID include bones and fractures (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs701006 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs701006 come from?

GWAS Catalog, Science 2019, PMID:31604244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Multiple sclerosis (rs701006). MyGeneLog™. https://www.mygenelog.com/variants/rs701006

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