Sensitive

Prostate cancer

near POU5F1B · rs6983561

Where this position leads

Condition: Prostate Cancer

rs6983561 Condition: Prostate Cancer Prostate Cancer Condition rs6983561 rs6983561 near POU5F1B

What the study found

Who was studied 1,033 Japanese ancestry cases, 1,042 Japanese ancestry controls, 1,043 Latino cases, 1,057 Latino controls; replicated in 1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls, 1,854 European ancestry cases, 3,748 European ancestry controls.

The effect Each copy of the C allele carried 1.87 times the odds of Prostate cancer (95% confidence interval 1.58-2.22); p = 4 × 10−13.

How common The C allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 8, band 8q24.21 — in an intron of CASC19.

What each result means

A/A No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs6983561

What is rs6983561?

rs6983561 is a single position in the genome, in or near the near POU5F1B gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6983561 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs6983561?

Subjects that appear in the title or abstract of the same papers as this rsID include alcohol and the flush (1 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs6983561 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6983561 come from?

GWAS Catalog, Cancer Epidemiol Biomarkers Prev 2012, PMID:22923026. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs6983561). MyGeneLog™. https://www.mygenelog.com/variants/rs6983561

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