Standard

Total concentration of lipoprotein particles

ANKDD1B · rs6886841

Where this position leads

Condition: Age-Related Macular Degeneration

rs6886841 Condition: Age-Related Macular Degeneration Age-Related Macular Degeneration Condition rs6886841 rs6886841 ANKDD1B

What the study found

Who was studied 98,316 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.00106 higher (95% confidence interval 0.00083-0.0013); p = 2 × 10−19.

How common The C allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 5, band 5q13.3 — in an intron of ANKDD1B.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Total concentration of lipoprotein particles compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Total concentration of lipoprotein particles.
T/T Published research associates this genotype with typical/baseline likelihood of Total concentration of lipoprotein particles — no copies of the reported risk allele.
Source

Questions about rs6886841

What is rs6886841?

rs6886841 is a single position in the genome, in or near the ANKDD1B gene. Published research associates it with total concentration of lipoprotein particles. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6886841 linked to?

On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.

Does having rs6886841 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6886841 come from?

GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total concentration of lipoprotein particles (rs6886841). MyGeneLog™. https://www.mygenelog.com/variants/rs6886841

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