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Monocyte count

MGAT4B · rs6883116

Where this position leads

Conditions: Blood Cell Counts, Monocyte Count

rs6883116 Condition: Blood Cell Counts Blood Cell Counts Condition Condition: Monocyte Count Monocyte Count Condition rs6883116 rs6883116 MGAT4B

What the study found

Who was studied 521,594 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.018 SD unit lower (95% confidence interval 0.014-0.022); p = 8 × 10−21.

How common The C allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 5, band 5q35.3 — in an intron of MGAT4B.

What each result means

C/C Two copies of the version the research linked to Monocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Monocyte count. That is a smaller link than two copies.
T/T No copy of the version the research linked to Monocyte count. This is the starting point the study compared everyone against.
Source

Questions about rs6883116

What is rs6883116?

rs6883116 is a single position in the genome, in or near the MGAT4B gene. Published research associates it with monocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6883116 linked to?

On MyGeneLog this position is linked to Blood Cell Counts, Monocyte Count. The research behind each link, and its sources, are set out on that condition page.

Does having rs6883116 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6883116 come from?

GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Monocyte count (rs6883116). MyGeneLog™. https://www.mygenelog.com/variants/rs6883116

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