Standard
PR interval
SCN10A · rs6800541
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of PR interval compared to the general population. (GWAS Catalog, Nat Genet 2010, PMID:20062060)
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with PR interval. (GWAS Catalog, Nat Genet 2010, PMID:20062060)
T/T
Published research associates this genotype with typical/baseline likelihood of PR interval — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2010, PMID:20062060)
Source
Genome-wide association study of PR interval
Pfeufer A,
van Noord C,
Marciante KD,
Arking DE,
Larson MG,
Smith AV,
Tarasov KV,
Müller M,
Sotoodehnia N,
Sinner MF,
Verwoert GC,
Li M
and 53 more — show all
Kao WH,
Köttgen A,
Coresh J,
Bis JC,
Psaty BM,
Rice K,
Rotter JI,
Rivadeneira F,
Hofman A,
Kors JA,
Stricker BH,
Uitterlinden AG,
van Duijn CM,
Beckmann BM,
Sauter W,
Gieger C,
Lubitz SA,
Newton-Cheh C,
Wang TJ,
Magnani JW,
Schnabel RB,
Chung MK,
Barnard J,
Smith JD,
Van Wagoner DR,
Vasan RS,
Aspelund T,
Eiriksdottir G,
Harris TB,
Launer LJ,
Najjar SS,
Lakatta E,
Schlessinger D,
Uda M,
Abecasis GR,
Müller-Myhsok B,
Ehret GB,
Boerwinkle E,
Chakravarti A,
Soliman EZ,
Lunetta KL,
Perz S,
Wichmann HE,
Meitinger T,
Levy D,
Gudnason V,
Ellinor PT,
Sanna S,
Kääb S,
Witteman JC,
Alonso A,
Benjamin EJ,
Heckbert SR
Nature genetics · 2010 · PMID 20062060 · open access
Questions about rs6800541
What is rs6800541?
rs6800541 is a single position in the genome, in or near the SCN10A gene. Published research associates it with pr interval. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6800541 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6800541 come from?
GWAS Catalog, Nat Genet 2010, PMID:20062060. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants