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Who was studied 388,538 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0149 lower (95% confidence interval 0.0098-0.02); p = 2 × 10−8.
How common The T allele had a frequency of about 14% in the people studied.
Where it sits Chromosome 3, band 3p24.3 — in an intron of SATB1-AS1.
What each result means
G/GPublished research associates this genotype with typical/baseline likelihood of Subjective well-being (MTAG) — no copies of the reported risk allele.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Subjective well-being (MTAG).
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Subjective well-being (MTAG) compared to the general population.
Nature genetics · 2018 · PMID 29292387 · open access
Questions about rs6787782
What is rs6787782?
rs6787782 is a single position in the genome, in or near the near SATB1 gene. Published research associates it with subjective well-being (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6787782 linked to?
On MyGeneLog this position is linked to Depression (Self-Reported Symptoms). The research behind each link, and its sources, are set out on that condition page.
Does having rs6787782 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6787782 come from?
GWAS Catalog, Nat Genet 2018, PMID:29292387. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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