Standard

Refractive error

near CREB1 · rs67802215

Where this position leads

Condition: Myopia

rs67802215 Condition: Myopia Myopia Condition rs67802215 rs67802215 near CREB1

What the study found

Who was studied 1,495,159 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0115 SD unit higher (95% confidence interval 0.0074-0.0156); p = 4 × 10−8.

How common The T allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 2, band 2q33.3 — in an intron of MYOSLID-AS1.

What each result means

C/C No copy of the version the research linked to Refractive error. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Refractive error. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Refractive error. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs67802215

What is rs67802215?

rs67802215 is a single position in the genome, in or near the near CREB1 gene. Published research associates it with refractive error. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs67802215 linked to?

On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.

Does having rs67802215 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs67802215 come from?

GWAS Catalog, Nature genetics 2026, PMID:42009823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Refractive error (rs67802215). MyGeneLog™. https://www.mygenelog.com/variants/rs67802215

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