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Sulfotransferase family cytosolic 1B member 1 levels

F5 · rs6701330

Where this position leads

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.411 higher (95% confidence interval 0.38-0.44); p = 2 × 10⁻²⁰⁰.

How common The T allele had a frequency of about 67% in the people studied.

Where it sits Chromosome 1, band 1q24.2 — in an intron of F5.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Sulfotransferase family cytosolic 1B member 1 levels — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Sulfotransferase family cytosolic 1B member 1 levels.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Sulfotransferase family cytosolic 1B member 1 levels compared to the general population.

Source

Mapping the proteo-genomic convergence of human diseases

Pietzner M, Wheeler E, Carrasco-Zanini J, Cortes A, Koprulu M, Wörheide MA, Oerton E, Cook J, Stewart ID, Kerrison ND, Luan J, Raffler J

and 9 more — show all

Arnold M, Arlt W, O'Rahilly S, Kastenmüller G, Gamazon ER, Hingorani AD, Scott RA, Wareham NJ, Langenberg C

Science (New York, N.Y.) · 2021 · PMID 34648354

Questions about rs6701330

What is rs6701330?

rs6701330 is a single position in the genome, in or near the F5 gene. Published research associates it with sulfotransferase family cytosolic 1b member 1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs6701330 affect how medicines work?

F5 carries pharmacogenomic findings for Combined hormonal contraceptives. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs6701330 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6701330 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sulfotransferase family cytosolic 1B member 1 levels (rs6701330). MyGeneLog™. https://www.mygenelog.com/variants/rs6701330

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