Standard

Triglycerides

MSL2L1 · rs645040

Where this position leads

Condition: High Triglycerides

rs645040 Condition: High Triglycerides High Triglycerides Condition rs645040 rs645040 MSL2L1

What the study found

Who was studied 96,598 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 2.22 mg/dL lower (95% confidence interval 1.34-3.1); p = 3 × 10−8.

How common The G allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 3, band 3q22.3 — between genes, 1.8 kb from RPL31P23.

What each result means

G/G Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
T/T No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs645040

What is rs645040?

rs645040 is a single position in the genome, in or near the MSL2L1 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs645040 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs645040?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs645040 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs645040 come from?

GWAS Catalog, Nature 2010, PMID:20686565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides (rs645040). MyGeneLog™. https://www.mygenelog.com/variants/rs645040

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