C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Glaucoma (primary open-angle) compared to the general population.
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Glaucoma (primary open-angle).
G/GPublished research associates this genotype with typical/baseline likelihood of Glaucoma (primary open-angle) — no copies of the reported risk allele.
Nature communications · 2018 · PMID 29891935 · open access
Questions about rs6434068
What is rs6434068?
rs6434068 is a single position in the genome, in or near the FMNL2 gene. Published research associates it with glaucoma (primary open-angle). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6434068 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs6434068 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6434068 come from?
GWAS Catalog, Nat Commun 2018, PMID:29891935. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.