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Monocyte count

near MIR7702 · rs62569864

Where this position leads

Conditions: Blood Cell Counts, Monocyte Count

rs62569864 Condition: Blood Cell Counts Blood Cell Counts Condition Condition: Monocyte Count Monocyte Count Condition rs62569864 rs62569864 near MIR7702

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−18, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 38,000 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.105 higher (95% confidence interval 0.081-0.129); p = 2 × 10−18.

Where it sits Chromosome 9, band 9q31.3 — between genes, 7.2 kb from MIR7702.

What each result means

A/A No copy of the version the research linked to Monocyte count. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Monocyte count. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Monocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source
Genetic architecture of routinely acquired blood tests in a British South Asian cohort
Jacobs BM, Stow D, Hodgson S, Zöllner J, Samuel M, Kanoni S, Bidi S, Walter K, Langenberg C, Dobson R, Finer S, Morton C
and 5 more — show all
Siddiqui MK, Martin HC, Pietzner M, Mathur R, van Heel DA
Genes & Health Research Team
Nature communications · 2024 · PMID 39414775 · open access

Questions about rs62569864

What is rs62569864?

rs62569864 is a single position in the genome, in or near the near MIR7702 gene. Published research associates it with monocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs62569864 linked to?

On MyGeneLog this position is linked to Blood Cell Counts, Monocyte Count. The research behind each link, and its sources, are set out on that condition page.

Does having rs62569864 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62569864 come from?

GWAS Catalog, Nature communications 2024, PMID:39414775. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Licensed CC BY-NC 4.0: free to read, share and adapt for non-commercial use, naming MyGeneLog™ and linking the exact page. Commercial use, including training or serving a commercial AI system, needs a licence — https://www.mygenelog.com/license

Monocyte count (rs62569864). MyGeneLog™. https://www.mygenelog.com/variants/rs62569864

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