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Hay fever and/or eczema

HLA-DQA1 · rs62404084

Where this position leads

Condition: Hay Fever And/or Eczema

rs62404084 Condition: Hay Fever And/or Eczema Hay Fever And/or Eczema Condition rs62404084 rs62404084 HLA-DQA1

What the study found

Who was studied 84,034 European ancestry cases, 239,773 European ancestry controls.

The effect Each copy of the C allele carried 1.11 times the odds of Hay fever and/or eczema (95% confidence interval 1.1-1.13); p = 1 × 10−43.

How common The C allele had a frequency of about 81% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — inside HLA-DQA1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hay fever and/or eczema compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hay fever and/or eczema.
T/T Published research associates this genotype with typical/baseline likelihood of Hay fever and/or eczema — no copies of the reported risk allele.
Source

Questions about rs62404084

What is rs62404084?

rs62404084 is a single position in the genome, in or near the HLA-DQA1 gene. Published research associates it with hay fever and/or eczema. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs62404084 linked to?

On MyGeneLog this position is linked to Hay Fever And/or Eczema. The research behind each link, and its sources, are set out on that condition page.

Does having rs62404084 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62404084 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:31361310. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hay fever and/or eczema (rs62404084). MyGeneLog™. https://www.mygenelog.com/variants/rs62404084

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