Standard

Glaucoma (low intraocular pressure)

GMDS · rs62391632

Where this position leads

Condition: Glaucoma

rs62391632 Condition: Glaucoma Glaucoma Condition rs62391632 rs62391632 GMDS

What the study found

Who was studied 1,886 European ancestry cases, 15,151 European ancestry controls, 1,315 East Asian ancestry cases, 32,649 East Asian ancestry controls, 46 Sub-Saharan African ancestry cases, 197 Sub-Saharan African ancestry controls.

The effect Each copy of the T allele carried 0.76 times the odds of Glaucoma (low intraocular pressure) (95% confidence interval 0.69-0.84); p = 2 × 10−11.

Where it sits Chromosome 6, band 6p25.3 — in an intron of GMDS.

What each result means

G/G No copy of the version the research linked to Glaucoma (low intraocular pressure). This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Glaucoma (low intraocular pressure). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Glaucoma (low intraocular pressure). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs62391632

What is rs62391632?

rs62391632 is a single position in the genome, in or near the GMDS gene. Published research associates it with glaucoma (low intraocular pressure). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs62391632 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs62391632 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62391632 come from?

GWAS Catalog, Nature communications 2021, PMID:33627673. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glaucoma (low intraocular pressure) (rs62391632). MyGeneLog™. https://www.mygenelog.com/variants/rs62391632

← See all variants